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What are the symptoms of chronic uremia?

Updated: Friday, Jan 08,2010, 3:36:40 PM
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What are the symptoms of chronic uremia?

Due to chronic uremia is a systemic multi-organ damage, so a wide variety of clinical manifestations:

Water-electrolyte metabolic disorders of chronic renal failure renal regulation of water and electrolyte disorders caused by hypothyroidism, or a series of symptoms such as edema, hypertension, pulmonary edema, cerebral edema, particularly hyperkalemia can directly lead to deaths.

Acidosis of chronic renal failure which is the typical symptoms of renal tubular emission is mainly attributable to a drop acid functionality.

Other symptoms of poisoning

Gastrointestinal symptoms: Due to gastrointestinal edema, anemia, resulting from too much ammonia, can cause nausea, vomiting, intermittent diarrhea, severe cases can cause gastrointestinal bleeding.

Cardiovascular system: hypertension, uremic pericarditis, uremic cardiomyopathy can cause heart failure and so on.

Respiratory: Due to pulmonary congestion, edema, pulmonary capillary permeability leading to increased difficulty in breathing, cough sputum foam can hear the wet rales, and sometimes coughing up blood sputum.

Blood system: bone marrow suppression caused by hematopoietic dysfunction, manifested as anemia, bleeding tendency, often bleeding gums, subcutaneous ecchymosis, hematemesis hematochezia and so on.

Nervous system: the majority of uremic patients have nervous system lesions, manifested in both lower extremities paresthesia, such as pins and needles, numbness, discomfort, muscle strength decline in late may have seizures or epilepsy.

Bone and the motor system: Due to calcium, phosphorus and vitamin D metabolism to reduce intestinal absorption, causing renal osteodystrophy, such as osteomalacia, pathological fracture and bone sclerosis.

Skin manifestations: skin itching is the most common symptoms, while dry skin, a small number of patients seen white urea cream skin.

Gonadal dysfunction: women may have to reduce menstruation, menstrual irregularity or amenorrhea, men may have impotence, low sperm and reduced plasma testosterone.

The immune system: immune dysfunction, infection and cancer incidence rate is higher than other groups.  metabolic abnormalities: protein, carbohydrate and fat metabolism are not normal.

Tags: uremia Chronic

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