Psoriasis is a chronic (long lasting) skin disease and inflammation of the expansion of between 2 and 2.6 percent of the population of the United States or carriers are between 5.8 and 7.5 million people. Although the disease occurs in all ages, affects mostly adults. It seems almost equally in men and women. Psoriasis occurs when skin cells quickly rise from their origin to the surface of the skin and accumulate on the surface before they have a chance to mature. Usually this movement (also called turnover) takes about a month, but in psoriasis will be published within a few days. In typical form, cover the results of thick plaque psoriasis, skin redness (inflammation of silver flakes). These patches, which are sometimes referred to as plaques, usually itch or feel sore. Most commonly found on elbows, knees, other parts of the legs, scalp, back, face, palms and soles but can occur on skin anywhere on the body. The disease can also affect the nails, claws and soft tissues of the genitals and mouth. Although it is not uncommon for the skin around affected joints nut to crack, approximately 1 million people with psoriasis experience joint inflammation that causes the symptoms of arthritis. This condition is called psoriatic arthritis.
Psoriasis is a skin disorder driven by the immune system, particularly in a subset of white blood cells such as T-cells. Normally, T cells help protect the body from infections and diseases. In the case of psoriasis, T cells act is wrong, and as active as other immune reactions that cause inflammation and activation of skin cells. In approximately one third of cases, no family history of psoriasis. Researchers have a large number of families studied in psoriasis and identified genes in question is the impact on health. (Genes govern every bodily function and determine the hereditary characteristics from parents to take kids. ) People with psoriasis may find that there are times when their skin worsens, then improves. Infections can be treated shoots, stress and changes in climate that dry the skin. Also, some medications can be prescribed for high blood pressure, including lithium and beta blockers, which cause an outbreak or worsen the disease.
How is psoriasis?
Doctors in general, to treat psoriasis in steps based on the severity of the disease, the size of the affected areas, type of psoriasis, and patient response to initial treatment. This is sometimes referred to as 1-2-3 approach . In step 1, medicines for the skin (topical treatment) applied. Step 2 uses light treatments (photo therapy). Step 3 involves taking medicines by mouth or by injection, the whole immune system (to deal with the so-called systemic therapy).
Over time, affected skin can become resistant to treatment, especially when using topical corticosteroid's. Even a treatment that works very well, a person has little effect on another. Thus, doctors often use trial and error, a treatment that works, and may resort to treatments periodically (eg every 12 to 24 months) if the treatment does not work or have side effects.
Some people with moderate to severe psoriasis may require counseling or participation in a support group for the benefit of children conscious about their appearance or relieve psychological distress resulting from fear of rejection.
What are some promising areas of psoriasis research?
Progress has been made in understanding the inheritance of psoriasis. The number of genes involved in psoriasis are already known or suspected. ) In a multi factorial disease (including genes, environment and other factors that may vary in one or more genes to produce higher probability of disease. Researchers are still studying the genetics of psoriasis. Since the discovery of that inflammation in psoriasis was caused by T cells, researchers are studying new treatments that quiet immune system reactions in the skin. Among these treatments, the activity of T cells or block cytokines (proteins that promote inflammation blocks) in. Some of these drugs are awaiting approval by the U.S. Food and Drug Administration (FDA).
Advances in laser technology allows doctors to experiment with laser light treatment of localized plaques. A UVB laser was recently tested in a study in several medical centers. Although it was found that the improvement of the skin, this treatment is not possible side effects. In some patients, is inflammation of the skin, blisters, or discolored following treatment.