(1), nipple discharge, especially bloody discharge, greater co-exist with breast cancer, particularly in women over the age of 50 appears bloody discharge, about half of the above may be malignant.
(2) The limitations of thickening of the breast glands, which is clinically and even for common signs of but not taken seriously. Such circumstances such as appear in non-menopausal women, in particular with the menstrual cycle, some the size of changes, mostly physiological. If the thickening of the long-term existence of the organization, has nothing to do with the menstrual cycle, or the increasingly thickening and scope of the increase, particularly in post-menopausal women, it must be stressed.
(3)nipple erosion, after repeated topical treatment ineffective, multi-Paget's disease should be considered for the high rate of smear-positive, should be a timely diagnosis.
(4) breast pain, in pre-menopausal women, in particular with the menstrual cycle changes, the degree of pain with or different light or heavy changes, mostly physiological. If pain is limited, there is a fixed location, has nothing to do with the menstrual cycle or post-menopausal women, should pinpoint the cause.
(5) unknown causes areola skin edema, nipple retraction, as well as the limitations of the breast skin, depression, etc., required careful investigation.