Gonorrhea is characterized by invasion of mucous membranes, to the reproductive, urinary system and the mucous membrane of transitional cell-based columnar epithelium. The skin of squamous epithelium, a certain resistance to the gonococcus. Gonococcus Hi wet, afraid of dry, away from the body completely dry after 2 hours under a death, in micro-wet underwear, towels, bedding can be to survive 10 to 17 hours, in the toilet seat board can survive 18 hours) General disinfectant or the soap so that it can rapidly inactivated.
Modes of transmission:
1. Sexually transmitted infections as the main mode of transmission for adults gonorrhea 99% ~ 100% transmission is possible.
2. Indirect contact with the infection mainly occurs in young girls access to contaminated clothing, buckets and so on.
3. Reproductive tract infection during childbirth when the fetus through the soft birth canal is infected.
Gonococcus infection through sexual intercourse, sexual secretions when gonococcus invasion urethra, cervix, etc., breeding and disease-causing bacteria on the premises, and may spread upward along the reproductive tract mucosa. Predilection sites for the paraurethral glands, cervix, Bartholin's gland, etc..
Clinical manifestations: The incubation period is 3 to 7 days, because 60% ~ 80% of women infected with gonorrhea after the asymptomatic, often overlooked. In symptomatic patients, earlier confined to lower genital tract, urinary tract, and subsequently on the development of the disease involving the reproductive tract. Two kinds of sub-acute and chronic pathology.
1. Acute gonorrhea
(1) The lower genital tract infection: the first symptoms are often painful urination, frequent urination, difficulty urinating and other symptoms of acute urethritis. At the same time there is a yellow purulent leucorrhea increased, vulva burning.
(2) on reproductive tract infections: lower genital tract gonococcal infections, if untreated, about 10% ~ 17% of patients may occur on the reproductive tract infections; or because the potential in the cervix of the gonococcus in menstruation, after menstruation (especially with sexual intercourse persons), miscarriage, intrauterine operation or post-natal and other incentives, then spread upward along the reproductive tract mucosa, causing impatient endometritis, acute salpingitis, and further development of pyosalpinx, tubal ovarian abscess, pelvic abscess, diffuse peritonitis resulting in toxic shock and other serious consequences.
(3) Disseminated gonorrhea: about 1% of the reproductive tract infections gonococcus can be transmitted through blood lines, causing systemic gonococcal disease, known as the spread of gonorrhea. Manifested as rash, due to the peripheral nervous system can occur by a variety of gonococcal lipopolysaccharide neuralgia. In addition, arthritis can also occur, meningitis, pleurisy, pneumonia, endocarditis, pericarditis, osteomyelitis, myositis, etc. as well as the most serious gonococcal sepsis, there chills, fever, whole body symptoms of poisoning.
2. Chronic gonorrhea infection without treatment or inadequate treatment may be turning into a chronic gonorrhea. Manifested as chronic urethritis, paraurethral pancreatitis, vestibular pancreatitis, chronic cervicitis, chronic salpingitis, hydrosalpinx and so on, in chronic gonorrhea, gonococcus although not present in the genital tract secretions, but may be lurking in the long term paraurethral glands, Bartholin's gland or cervical mucous glands deep, as a lesion caused by recurrent acute episodes.