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What is scleroderma

Updated: Wednesday, Feb 10,2010, 3:46:34 PM
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Scleroderma is a systematic hardening of the skin and the connective tissue diseases. Chinese literature, "the skin numb." Clinical swelling of the skin, hair hard, late atrophy may be associated with bone damage characterized dirty. The incidence of the major connective tissue disease, second only to systemic erythroderma can occur at any age, but more common in middle-aged women. Men can also occur, sex ratio of about 1:3, an incidence rate of The connective tissue in the main, second only to systemic lupus erythematosus.


Scleroderma can occur at any age child, apparatus, mostly in 1l a 20 years old, women are more open to involving all parts of the skin. Chronic course, a few self-limiting, and the remaining traces of shrinkage.

Early lesions of purple spots, and slowly expanded to - a certain extent that is long-term change, color gradient light, hard skin can be presented guttate, patchy, ribbon distribution, vellus hair shedding, local non-sweating the late skin atrophy, pigment faded.

Systemic scleroderma

Systemic scleroderma can occur at any age, with female patients as the more common, skin lesions often symmetry or white from the extremities to the center to the end, head, face, body footer began to increase slowly progressive expansion may be violations of internal organs various organs, but the digestive system, respiratory system more common. Rapid progress of the disease, the prognosis is poor, there are life-threatening.

Prodromal symptoms prior to the onset often - Rules of fever, joint pain, or neuralgia, weight loss, Raynaud's phenomenon and the most common, mainly mild cyanosis of the fingers until the typical color changes, such as pale, bruising and redness. Raynaud's phenomenon may be earlier than the lesions of a few months or years, but many times can automatically ease relapse. Women are often irregular menstruation, or uterine disease, or history of reproductive failure such as insincere.

Lesions can be divided into swelling period, hardening period, contraction period. Swelling period: in the lesion site appeared Mi Fa Zhi Wen erythema and substantial swelling, according to the non-sag, the skin tight shiny like waxy, normal wrinkles disappear, showing yellow or brown, or pale or normal skin color. Prior to the onset often feel abnormal, such as tingling, micro-pain, numbness, or ant-line flu. Hardening period: the skin graded edema at the school, showing yellow wax and the sunlight, the skin can not be hand-Nian Qi, may be associated with pigment abnormalities (pigmentation and depigmentation co-exist), perception retardation, loss of hair. Contraction period: thinning of the skin atrophy, such as parchment-like or stiff as leather, the course of time into a board-like hardening.

Special type scleroderma

Acral sclerosis is a species of special types of systemic scleroderma. The clinical features of skin sclerosis instrument issued in the extremities, can affect the face, Raynaud's phenomenon of apparent limb Swiss skin sclerosis, atrophy an extent which rendered even hard, deformity, activity barriers, and may happen that (toe) end of ulcers, gangrene . Or even fall off. Internal organs generally not involved, slow progression of steamed bread, and sometimes natural recovery. Some can be turned into systematic violations of visceral scleroderma.

Benign MS is a relatively benign limb shaped Swiss sclerosis, the clinical to the skin of calcium Shen persons, Raynaud's phenomenon, refers to (toe) skin sclerosis, telangiectasia is characterized by four types of performance, meaning that cRsT Syndrome (in order to four kinds of performance in the first name in English letters). If accompanied by esophageal dysfunction, claimed cREsT syndrome. Slow course of steamed bread, a non-aggression Yin visceral system, a better prognosis.

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