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Blood test can predict risk of lung cancer

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Updated: Tuesday, Oct 20,2009, 8:54:46 PM
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Studies have shown that some people are very sensitive to the carcinogenic effects of smoking. This also identify those at higher risk of lung cancer incidence in smokers has provided a new way to present lung cancer cause of death in the United States ranks in the first place.

 
New York, Dr. Frederica Perera of Columbia University and his colleagues pointed out that "the study is of great significance, because it prompts the blood biomarkers to predict the occurrence of lung cancer."

According to U.S. researchers reported that blood levels of certain compounds, the higher the possibility of lung cancer in smokers is far greater than those with lower levels of the corresponding compounds smokers.

Researchers found that white blood cells due to polycyclic aromatic hydrocarbons (PAHs) carcinogenic substances such as DNA damage caused by higher levels of smokers of 1 to 13 years after being diagnosed with lung cancer risk is likely to increase three-fold, but these compounds with of lung cancer occurred after quitting smoking is not relevant. The results were published in the latest issue of "Cancer Research" journal.

Dr. Perera analysis of blood samples collected 13 years ago, and compared 173 healthy male and 89 were diagnosed as lung cancer among men with the DNA content of the carcinogenic compounds.

Higher levels of the compound in the blood of smokers, often due to exposure to PAHs and other carcinogens in the environment caused. And those in the blood of smokers with lower levels of the compound compared to their risk of lung cancer was significantly higher, but over time, cancer risk is increasing.

Cigarette smoke contains a higher concentration inside the PAHs, while it can also pollute the air, just as outdoor automobile exhaust, power plants, air pollution caused by cooking, like cooking. Barbecue food can also generate PAHs. These compounds can be combined DNA, causing cancer-causing mutations.


Tags: Cancer lung Blood

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