Osteoporosis is a common disease of the elderly . Among postmenopausal osteoporosis is primary osteoporosis is the most common form , its prevalence rate of 30 % to 50 %. Because of its slow onset, often overlooked , it was called the silent epidemic.
To clarify the effects of acupuncture on osteoporosis in ovariectomized rat model of estrogen levels and bone density , and to explore the mechanism of acupuncture treatment of osteoporosis , the researchers healthy female SD rats were randomly divided into 4 groups of 32 normal control group, model group, acupuncture group and western medicine group , each eight . In addition to the normal group, other groups were conducted Abstract manufacturing model of osteoporosis ovarian surgery . Acupuncture needle into the group with the 30th bilateral Zusanli Sanyinjiao connect EA stimulation frequency 1 ~ 3Hz, the waveform of density wave , pulse width 1ms, the intensity of 0.7 ~ 1.0mA, once a day, every EA continued for 20 minutes medicine group fed at a concentration of 5% Nylestriol , each fed 5mL / week , other times fed normal saline group and model group were fed daily while saline . After 8 weeks eyeball blood , take the left femur . By dual energy X-ray absorptiometry to measure bone density in rat femur , serum estradiol levels by ELISA.
The results showed that the normal group, acupuncture group and western medicine group compared with the model group , bone mineral density was significantly higher (P <0.01), significantly higher serum estradiol (P <0.05), significantly lower body weight (P <0.01). Normal group, western medicine group , no between BMD and serum estradiol acupuncture group significant difference (P> 0.05).
According to Traditional Chinese Medicine, Xijing Hospital, Associate Professor Wang Changhai , an important manifestation of osteoporosis is reduced bone mass , bone mass is to evaluate the degree of bone loss and the effects of the key indicators of drug prevention . World Health Organization definition of osteoporosis is bone mineral density of at least 2.5 standard deviation than the average young adult of the same sex is low. Studies have shown that a decrease in femoral neck BMD standard deviation for each of its increased fracture risk 2.6 times . The study results show that the model group femur lower than normal group , indicating reduced bone mineral density after removal of the ovaries , significantly increases the risk of fractures , after the acupuncture treatment , bone mineral density was significantly higher than the model group , reducing the fracture dangerous. Also confirmed the role of acupuncture therapy to improve bone density and medicine similar.
An important reason for the occurrence of post-menopausal osteoporosis is due to estrogen deficiency .
Our studies show that the model is lower than normal serum estradiol group after acupuncture treatment , serum estradiol was significantly higher than the model group , indicating that acupuncture can not only reduce high serum estrogen levels in rats , but also increase in serum estrogen levels too low , that acupuncture has a two-way adjustment for the effects of estrogen . The results also demonstrated that acupuncture can significantly reduce body weight , which provided some experimental evidence for acupuncture treatment of postmenopausal obesity.