Multiple myeloma does not always cause symptoms in its early stages. But possible symptoms can include
* Kidney problems caused by the paraproteins produced by the myeloma cells. Kidney damage can cause tiredness and anaemia.
* Repeated colds, coughs and other infections (particularly chest infections) because of a shortage of normal antibodies.
* Weakening of the bones by the myeloma cells, which may increase the risk of fractures.
* Loss of appetite, feeling sick, constipation, depression and drowsiness caused by too much calcium in the blood (hypercalcaemia). The excess calcium is released into the blood from the damaged bones.
* Unexplained bruising and abnormal bleeding (for example, nosebleeds or bleeding gums) because the number of platelets in the blood has decreased.
* Pins and needles, numbness, tingling or weakness in the feet or legs; or difficulty passing urine or opening the bowels. Any of these symptoms could mean that a myeloma tumour is pressing on the spinal cord (known as cord compression). Contact your doctor immediately if you think that this may be happening to you.