Healthy egg and sperm combine, the normal uterus and fallopian tubes, an appropriate balance of chemical and biological environment and endocrine, are pregnant and maintaining pregnancy conditions, any of these factors may lead to abnormal miscarriage. Abortion is not only caused physical harm to patients would also bring the spirit of the fight against the family. Abortion occurred 3 consecutive times or more, medicine is called habitual abortion. Habitual abortion merely a symptom, but in this performance behind the hidden causes of disease, the most common causes are the following:
Genetic factors: family marriage, the couple either one or both chromosomal abnormalities, both husband and wife closer blood ties, the more easily the next generation of chromosomal abnormalities manifested as dominant, chromosome abnormalities embryos can not survive more than a result of abortion, there are also teratogenic, fetal growth retardation, Although the survival or chromosomal abnormalities, but showed dominant inheritance.
Uterine abnormalities: Congenital uterine malformations such as double uterine horn, saddle-shaped uterus, the uterus is too small, intrauterine adhesions, uterine fibroids, also may cause habitual abortion. Uterus is Yunluan implantation, development, growth of the premises is the embryonic development of soil, the uterus is not an exception to the normal development of Yunluan will cause miscarriage and should therefore be actively treated. Uterine hypoplasia, the uterus is too small can be used estrogen therapy, commonly used DES 0.5mg ~ 1mg, daily one time, bedtime oral, from the 5th day of menstrual cycle, used in conjunction on the 20th, a total of 3 to 4 cycles; can also be used to stimulate foreign body law, such as placing a small IUD within the uterus, prompting the uterus increases; sometimes be necessary for surgical, such as the removal of intrauterine adhesions, uterine plastic surgery, myomectomy and so on.
Luteal phase defect: ovarian rupture after ovulation, luteal formation, luteal secretion of progesterone and estrogen. Conception, the corpus luteum to maintain pregnancy, 4 to 6 months to start degradation, early pregnancy corpus luteum life span and its function is affected by human chorionic gonadotropin (HCG) role. Yunluan after implantation in the womb, from eggs to embryonic cells differentiated syncytiotrophoblast, decidua in contact with them will develop into the placenta, syncytiotrophoblast secretion of HCG will soon enter the matrix, so that luteal life expectancy, and to stimulate its synthesis progesterone to maintain pregnancy.
Maternal-fetal blood group incompatibility: The most common for the ABO blood group incompatibility, you rarely get a RH-based, MN system blood group incompatibility. If the blood group incompatibility between mother and fetus, fetal antigen from the fathers get into the mother's body to produce antibodies through the placenta into the fetal blood circulation, acting on the red blood cells, so that destruction of hemolysis, severe fetal death can, resulting in late abortion. In the ABO blood group incompatibility, the majority of pregnant women for the O-type blood, the husband of A, B or type AB blood type, if the fetal blood is A type or B type, is likely to occur late abortion, but the incidence of such cases is not high.
Cervical relaxation within the mouth: habitual late abortion often caused by the relaxation of the cervix within the mouth. As the surgical injury, few are congenital abnormalities caused by population expansion of the cervix, and uterus isthmus defects in the mid-pregnancy, amniotic fluid increased, the fetus grew up in increased intrauterine pressure, fetal sac inside the mouth from the cervical prominent, gradually reduce the cervical canal , expansion, when the pressure increased to a certain extent, all of a sudden rupture of membranes, resulting in fetal abortion discharged. Such repeated abortion, abortion occurred in accordance with the previous period, select 12 to 20 weeks of pregnancy uterine ligation within the mouth and after I tocolysis therapy, to full-term pregnancy has threatened labor or cesarean section was implemented again when removed suture.
Habitual abortion more complicated reasons, and only find out the reasons, in a targeted manner to achieve to meet the effects of the treatment, people with this disease, women should go to the hospital for a comprehensive system checks. After an abortion, especially ovarian and uterine hypoplasia dysfunction of women, preferably after three normal menstrual cycle after pregnancy, in order to have sufficient time to restore the body hormones and endometrial function.