Whenever clinical cases of neonatal jaundice and hemolytic anemia should think of glucose 6-phosphate dehydrogenase (G6PD) deficiency caused by neonatal jaundice, especially in non-high incidence, should pay attention. The clinical features of this disease is no jaundice at birth, and 24 hours after the jaundice began to appear, and there is evidence of hemolysis, liver and spleen enlargement. These can be differentiated from other properties of neonatal jaundice. Further trials for a variety of G6PD deficiency, can confirm the diagnosis.
Neonatal jaundice if hepatosplenomegaly, jaundice and anemia should be suspected might be the same kind of immunization or infection caused.
Isoimmunization ABO hemolytic disease occurs due to the mother's, jaundice and anemia at birth already exists. Mother's blood can be used for identification and related serology, anti-human globulin test and various tests related to G6PD deficiency, these two diseases to make a clear identification.